Obstructive laryngitis in dogs and cats
Nonneoplastic infiltration of the larynx with inflammatory cells can occur in dogs and cats, causing irregular proliferation, hyperemia, and swelling of the larynx. Clinical signs of an upper airway obstruction results. The larynx appears grossly neoplastic during laryngoscopy but is differentiated from neoplasia on the basis of the findings from the histopathologic evaluation of biopsy specimens. Inflammatory infiltrates can be granulomatous, pyogranulomatous, or lymphocytic-plasmacytic. Etiologic agents have not been identified.
This syndrome is poorly characterized and probably includes several different diseases. Some animals respond to glucocorticoid therapy. Prednisone (1.0 mg/kg given orally q12h) is used initially. Once the clinical signs have resolved, the dose of prednisone can be tapered to the lowest one that effectively maintains remission of clinical signs. Conservative excision of the tissue obstructing the airway may be necessary in animals with severe signs of upper airway obstruction or large granulomatous masses.
The prognosis varies, depending on the size of the lesion, the severity of laryngeal damage, and the responsiveness of the lesion to glucocorticoid therapy.
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This syndrome is poorly characterized and probably includes several different diseases. Some animals respond to glucocorticoid therapy. Prednisone (1.0 mg/kg given orally q12h) is used initially. Once the clinical signs have resolved, the dose of prednisone can be tapered to the lowest one that effectively maintains remission of clinical signs. Conservative excision of the tissue obstructing the airway may be necessary in animals with severe signs of upper airway obstruction or large granulomatous masses.
The prognosis varies, depending on the size of the lesion, the severity of laryngeal damage, and the responsiveness of the lesion to glucocorticoid therapy.
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