Regulation of reproduction in the male animal

The principle of reproduction in the male shows a pattern similar to that in the female. GnRH from the hypothalamus stimulates the release of FSH and LF (in the male formerly called ICSH=interstitial cell stimulating hormone). FSH acts directly on the seminiferous tubules of the testis (germ cells and Sertoli cells). Here spermatogenesis is stimulated by FSH. Sertoli cells produce inhibin, which has a negative feedback on FSH secretion by the pituitary gland.

LH stimulates the production of testosterone by the Leydig cells. Testosterone influences the Sertoli cells and is necessary for successful spermatogenesis. Furthermore, testosterone induces morphological changes and typical male behaviour. Testosterone has a negative feedback on the LH secretion by suppressing the pulsatile GnRH release from the hypothalamus. So in the male similar control systems, with stimulation and feedback loops, can be found as in female reproduction.

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