Renal effects in dogs and cats
Renal efferent glomerular arteriolar constriction, mediated by sympathetic stimulation and angiotensin II, helps maintain glomerular filtration in the face of reduced cardiac output and renal blood flow. Higher oncotic and lower hydrostatic pressures develop in the peritubular capillaries, enhancing the reabsorption of tubular fluid and sodium. Angiotensin II - mediated aldosterone release further promotes sodium and water retention. Continued activation of these mechanisms leads to clinical edema and effusions.
Afferent arteriolar vasodilatation mediated by endogenous prostaglandins and natriuretic peptides can partially offset the effects of efferent vasoconstriction, but progressive impairment of renal blood flow leads to renal insufficiency. Diuretics not iaconly can magnify azotemia and electrolyte loss, they also can further reduce cardiac output and activate the neurohormonal mechanisms.
We would love to hear your pet's story. Please add a comment.
Afferent arteriolar vasodilatation mediated by endogenous prostaglandins and natriuretic peptides can partially offset the effects of efferent vasoconstriction, but progressive impairment of renal blood flow leads to renal insufficiency. Diuretics not iaconly can magnify azotemia and electrolyte loss, they also can further reduce cardiac output and activate the neurohormonal mechanisms.
We would love to hear your pet's story. Please add a comment.
MORE VETERINARY ARTICLES
-
System venous and right heart filling pressures are reflected at the jugular veins in dogs and cats . These veins should not be distended wh...
-
Bronchoscopy is indicated for the evaluation of the major airways in animals with suspected structural abnormalities; for visual assessment...
-
The strength and regularity of the peripheral arterial pressure waves and the pulse rate are assessed by palpation of the femoral or other p...
-
Mucous membrane color and capillary refill time (CRT) are used to estimate the adequacy of peripheral perfusion. Normally the oral membranes...
-
Brand Name Heartgard Plus (Merial), Iverhart Plus (Virbac) Generic Name Ivermectin, Pyrantel pamoate What is the most important inform...
-
Canine Coronaviral Enteritis | Coronaviral Enteritis in Dogs Coronaviral enteritis in dogs occurs when coronavirus invades and destroys ma...
-
Canine Bronchitis | Bronchitis in Dogs Chronic bronchitis in dogs refers to long-term airway inflammation. There is generally a component ...
-
Renal enlargement is usually detected by physical examination or by abdominal radiography or by ultrasonography . A quick rule of thumb is ...
-
Canine Skin Disease | Skin Infections in Dogs Staphylococcus intermedius is the most common cause of pyoderma in dogs and cats. Deep py...
-
Dog Allergies | Allergies in Dogs Allergies in dogs are basically an immune system overreaction. The nasal cavity is an uncommon primary...
