Renal effects in dogs and cats
Renal efferent glomerular arteriolar constriction, mediated by sympathetic stimulation and angiotensin II, helps maintain glomerular filtration in the face of reduced cardiac output and renal blood flow. Higher oncotic and lower hydrostatic pressures develop in the peritubular capillaries, enhancing the reabsorption of tubular fluid and sodium. Angiotensin II - mediated aldosterone release further promotes sodium and water retention. Continued activation of these mechanisms leads to clinical edema and effusions.
Afferent arteriolar vasodilatation mediated by endogenous prostaglandins and natriuretic peptides can partially offset the effects of efferent vasoconstriction, but progressive impairment of renal blood flow leads to renal insufficiency. Diuretics not iaconly can magnify azotemia and electrolyte loss, they also can further reduce cardiac output and activate the neurohormonal mechanisms.
We would love to hear your pet's story. Please add a comment.
Afferent arteriolar vasodilatation mediated by endogenous prostaglandins and natriuretic peptides can partially offset the effects of efferent vasoconstriction, but progressive impairment of renal blood flow leads to renal insufficiency. Diuretics not iaconly can magnify azotemia and electrolyte loss, they also can further reduce cardiac output and activate the neurohormonal mechanisms.
We would love to hear your pet's story. Please add a comment.
MORE VETERINARY ARTICLES
-
The strength and regularity of the peripheral arterial pressure waves and the pulse rate are assessed by palpation of the femoral or other p...
-
System venous and right heart filling pressures are reflected at the jugular veins in dogs and cats . These veins should not be distended wh...
-
Pulmonary contusion in dogs and cats is caused by blunt trauma and is a common finding in animals that have been hit by cars. Hemorrhage in...
-
Renal enlargement is usually detected by physical examination or by abdominal radiography or by ultrasonography . A quick rule of thumb is ...
-
Mucous membrane color and capillary refill time (CRT) are used to estimate the adequacy of peripheral perfusion. Normally the oral membranes...
-
Thoracic auscultation in dogs and cats is used to identify normal heart sounds, determine the presence or absence of abnormal sounds, asses...
-
Signs and symptoms of syncope in dogs and cats . Cardiac output often becomes inadequate in animals with heart disease or heart failure , e...
-
Canine Leukemia | Leukemia in Dogs In dog leukemias constitute fewer than 10% of all hemolymphatic neoplasms and are therefore consider...
-
Dog Names Give a name to your dog The name you will choose for your dog is tied to your personality. It reflects the relationship you w...
-
The same general mechanisms that cause edema elsewhere in the body cause edema in the pulmonary parenchyma. Major mechanisms are decreased ...
