The mammal kidney
The kidney is a remarkable organ charged with a diverse set of responsabilities in maintaining the homeostasis of the body. In mammals, the two kidneys receive approximately 25% of the cardiac output. Not only must the kidney filter this blood in order to excrete metabolic waste, but it must also retrieve those filtered materials that are needed by the body, including low-molecular-weight proteins, water and a variety of electrolytes. It must recognize when water and specific electrolytes are present in excess and respond by failing to reabsorb or by secreting these substances.
It contributes substantially to the maintenance of acid-base homeostasis. In addition, the production and release of hormones by the kidney play a vital role in the control of systemic blood pressure and red blood cell production. In order to accomplish these tasks, the kidney is composed of an extensive variety of cell types, each endowed with an individual set of functions and design to respond as needed to a complex battery of direct and indirect signals. These cells are arranged in a particular pattern to form the functional unit of the kidney, the nephron. The nephron is composed of the glomerulus, where the blood is filtered, and various distinct segments of the renal tubule, where filtered substances are absorbed from and plasma components are secreted into the tubular fluid. In the cortex the nephrons join with the collecting duct system, which traverses the kidney and ends with the inner medullary collecting duct, where the final alterations of the tubular fluid take place in the formation of urine.
The specific functions of the kidney and the methods by which they are accomplished are quite complex. Most of the experimental evidence for what we believe about renal physiology has been obtained in the rat or the rabbit. Much of what is currently believed about renal physiology remains subject to revision and reinterpretation as more information is gathered.
We would love to hear your pet's story. Please add a comment.
It contributes substantially to the maintenance of acid-base homeostasis. In addition, the production and release of hormones by the kidney play a vital role in the control of systemic blood pressure and red blood cell production. In order to accomplish these tasks, the kidney is composed of an extensive variety of cell types, each endowed with an individual set of functions and design to respond as needed to a complex battery of direct and indirect signals. These cells are arranged in a particular pattern to form the functional unit of the kidney, the nephron. The nephron is composed of the glomerulus, where the blood is filtered, and various distinct segments of the renal tubule, where filtered substances are absorbed from and plasma components are secreted into the tubular fluid. In the cortex the nephrons join with the collecting duct system, which traverses the kidney and ends with the inner medullary collecting duct, where the final alterations of the tubular fluid take place in the formation of urine.
The specific functions of the kidney and the methods by which they are accomplished are quite complex. Most of the experimental evidence for what we believe about renal physiology has been obtained in the rat or the rabbit. Much of what is currently believed about renal physiology remains subject to revision and reinterpretation as more information is gathered.
We would love to hear your pet's story. Please add a comment.
MORE VETERINARY ARTICLES
-
Clinical signs of acute renal failure symptoms (ARF) are often nonspecific and include lethargy, depression, anorexia, vomiting , diarrhea...
-
The same general mechanisms that cause edema elsewhere in the body cause edema in the pulmonary parenchyma. Major mechanisms are decreased ...
-
Oral Pain 1. Fractured bones or teeth. 2. Trauma. 3. Periodontitis or caries (especially cats). 4. Osteomyelitis. 5. Other causes ...
-
The profile of the Golden Retriever may justify for you its reputation as a very good family pet. The Golden Retriever ranks the lowest of a...
-
1. Acetaminophen. 2. Antiarrythmics. 3. Anticonvulsants. 4. Antiinflammatories (nonsteroidal). 5. Barbiturates. 6. Benzocaine. 7. Chemothera...
-
Heartworm prophylaxis is indicated for all dogs living in endemic areas. Because sustained warm, moist conditions are important for heartwor...
-
Feline Leukemia Treatment - Treating Leukemia in Cats Avoiding contact with feline leukemia virus by housing cats indoors is the best form...
-
Renal efferent glomerular arteriolar constriction, mediated by sympathetic stimulation and angiotensin II, helps maintain glomerular filtrat...
-
Primary bone neoplasms are relatively common in dogs. Most primary bone tumors in dogs are malignant in that they usually cause death as a r...
-
Contaminated hands are the most common source of infectious disease transmission in the hospital environment. Fingernails of personnel havin...