Chemotherapy in dogs and cats
Chemotherapy in dogs and cats is primarily indicated for animals with systemic (e.g., lymphoma, leukemias) or metastatic neoplasms, although it can also be used for the management of nonresectable, chemoresponsive neoplasms that have historically proved refractory to radiotherapy or hyperthermia (primary chemotherapy). It can also be used as an adjuvant treatment after partial surgical debulking of a neoplasm (e.g., partial excision of an undifferentiated sarcoma) and is indicated for the control of micrometastatic disease after the surgical excision of a primary neoplasm (e.g., cisplatin, carboplatin or doxorubicin therapy after limb amputation in dogs with osteosarcoma; VAC after splenectomy for dogs with hemangiosarcoma).
Chemotherapy can also be administered intracavitarily in dogs and cats with malignant effusions or neoplastic involvement in the cavity/area in question (e.g., intrathecally administered cytosine arabinoside in dogs and cats with pleural carcinomatosis).
As a general rule, chemotherapy should not be used as a substitute for surgery, radiotherapy, or hyperthermia; nor should it be used in animals with severe underlying multiple-organ dysfunction because this increase the risk of systemic toxicity.
Chemotherapy can also be administered intracavitarily in dogs and cats with malignant effusions or neoplastic involvement in the cavity/area in question (e.g., intrathecally administered cytosine arabinoside in dogs and cats with pleural carcinomatosis).
As a general rule, chemotherapy should not be used as a substitute for surgery, radiotherapy, or hyperthermia; nor should it be used in animals with severe underlying multiple-organ dysfunction because this increase the risk of systemic toxicity.
MORE VETERINARY ARTICLES
-
The strength and regularity of the peripheral arterial pressure waves and the pulse rate are assessed by palpation of the femoral or other p...
-
System venous and right heart filling pressures are reflected at the jugular veins in dogs and cats . These veins should not be distended wh...
-
Pulmonary contusion in dogs and cats is caused by blunt trauma and is a common finding in animals that have been hit by cars. Hemorrhage in...
-
Renal enlargement is usually detected by physical examination or by abdominal radiography or by ultrasonography . A quick rule of thumb is ...
-
Mucous membrane color and capillary refill time (CRT) are used to estimate the adequacy of peripheral perfusion. Normally the oral membranes...
-
Thoracic auscultation in dogs and cats is used to identify normal heart sounds, determine the presence or absence of abnormal sounds, asses...
-
Signs and symptoms of syncope in dogs and cats . Cardiac output often becomes inadequate in animals with heart disease or heart failure , e...
-
Canine Leukemia | Leukemia in Dogs In dog leukemias constitute fewer than 10% of all hemolymphatic neoplasms and are therefore consider...
-
Dog Names Give a name to your dog The name you will choose for your dog is tied to your personality. It reflects the relationship you w...
-
The same general mechanisms that cause edema elsewhere in the body cause edema in the pulmonary parenchyma. Major mechanisms are decreased ...
