Good and bad cholesterol in dogs
Good and bad cholesterol dogs
High-density lipoprotein (HDL) is the smallest of the lipoprotein molecules and is synthesized primarily in the liver (and to a certain degree in enterocytes). HDL are involved in reverse cholesterol transport. HDL transfer free cholesterol from cell membranes to to the HDL molecule as cholesterol esters via an enzyme lecithin: cholesterol acyl transferase.
The cholesterol esters may be transferred to very low-density lipoproteins (VLDL) by cholesterol ester transfer protein to eventually form low-density lipoprotein (LDL), which provides cholesterol to peripheral cells. Alternatively, the cholesterol esters may be delivered to the liver in HDL for excretion as bile salts. Because HDL are capable of transporting cholesterol from the periphery to the liver for disposal, they are said to contain ”good cholesterol” because they transport cholesterol to the periphery where excess may result in arterial plaque and cardiovascular disease.
We would love to hear your pet's story. Please add a comment.
High-density lipoprotein (HDL) is the smallest of the lipoprotein molecules and is synthesized primarily in the liver (and to a certain degree in enterocytes). HDL are involved in reverse cholesterol transport. HDL transfer free cholesterol from cell membranes to to the HDL molecule as cholesterol esters via an enzyme lecithin: cholesterol acyl transferase.
The cholesterol esters may be transferred to very low-density lipoproteins (VLDL) by cholesterol ester transfer protein to eventually form low-density lipoprotein (LDL), which provides cholesterol to peripheral cells. Alternatively, the cholesterol esters may be delivered to the liver in HDL for excretion as bile salts. Because HDL are capable of transporting cholesterol from the periphery to the liver for disposal, they are said to contain ”good cholesterol” because they transport cholesterol to the periphery where excess may result in arterial plaque and cardiovascular disease.
We would love to hear your pet's story. Please add a comment.
MORE VETERINARY ARTICLES
-
The strength and regularity of the peripheral arterial pressure waves and the pulse rate are assessed by palpation of the femoral or other p...
-
System venous and right heart filling pressures are reflected at the jugular veins in dogs and cats . These veins should not be distended wh...
-
It is easier for the body to prevent edema fluid from forming that it is to mobilize existing fluid. The initial management of treating pulm...
-
Signs and symptoms of syncope in dogs and cats . Cardiac output often becomes inadequate in animals with heart disease or heart failure , e...
-
Bronchoscopy is indicated for the evaluation of the major airways in animals with suspected structural abnormalities; for visual assessment...
-
Renal enlargement is usually detected by physical examination or by abdominal radiography or by ultrasonography . A quick rule of thumb is ...
-
Dog distemper symptoms - Canine distemper Widespread vaccination has substantially decreased the incidence of dog distemper virus infect...
-
Cyclophosphamide in dogs Cyclophosphamide (Cytoxan, Mead Johnson, Evansville, Ind) is a very effective immunosuppressive agent for induci...
-
Canine Skin Disease | Skin Infections in Dogs Staphylococcus intermedius is the most common cause of pyoderma in dogs and cats. Deep py...
